Basics of Linkage and Gene Mapping
نویسنده
چکیده
Basics of Linkage and Gene Mapping ......................................................................45 Linkage....................................................................................................................45 Linkage disequilibrium ............................................................................................47 Mapping functions ...................................................................................................48 Mapping of genetic markers .....................................................................................50 Estimation of the recombination fraction ..............................................................50 Maximum likelihood estimation of linkage (recombination fraction).....................51 Testing for linkage: LOD scores...............................................................................52 Design of mapping ...................................................................................................54 References............................................................................................................54
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